Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957736 | 0.97 | HDAC4 (0.40) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL16950341 | 0.93 | HTR2C (0.36) | HDAC4HDAC2HDAC8KMODRD2 | |
| SCHEMBL16957285 | 0.81 | HDAC4 (0.45) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL27721455 | 0.79 | KMO (0.46) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL16957390 | 0.78 | HDAC4 (0.46) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL16961080 | 0.78 | HDAC4 (0.42) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL16960705 | 0.77 | HDAC4 (0.41) | HDAC4HDAC2HDAC8KMODRD2 | |
| SCHEMBL778529 | 0.77 | HDAC4 (0.63) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL7634263 | 0.77 | HDAC4 (0.47) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL16959967 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |