Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.34 |
| ▸ | MICA | Q29983 | 1/20 | 0.34 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953424 | 0.93 | HDAC4 (0.42) | HDAC4HDAC2HDAC8KMOSIGMAR1 | |
| SCHEMBL16957390 | 0.93 | HDAC4 (0.46) | HDAC4HDAC2HDAC8KMODRD2 | |
| SCHEMBL16959890 | 0.85 | ESR2 (0.33) | CYP3A4ESR1CYP2C9ESR2 | |
| SCHEMBL29256485 | 0.82 | SLC18A3 (0.44) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL30988828 | 0.82 | SLC18A3 (0.44) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL16956298 | 0.82 | HTR2C (0.36) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL29256486 | 0.82 | SLC18A3 (0.44) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL30988811 | 0.82 | SLC18A3 (0.44) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL18793787 | 0.81 | KMO (0.39) | HDAC4HDAC2HDAC8KMOSLC18A3 | |
| SCHEMBL29337379 | 0.81 | BCDIN3D (0.39) | HDAC4HDAC2HDAC8KMOSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |