Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481057 | 0.93 | LMNA (0.53) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL26162755 | 0.89 | LMNA (0.47) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL28680548 | 0.85 | ALDH1A1 (0.53) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL2655486 | 0.82 | LMNA (0.61) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL7870569 | 0.82 | ALDH1A1 (0.48) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL16950934 | 0.81 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL4739763 | 0.81 | ALDH1A1 (0.47) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL16952642 | 0.81 | ALDH1A1 (0.49) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL6828757 | 0.81 | GAA (0.50) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL8127577 | 0.81 | LMNA (0.46) | LMNATSHRALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |