Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958582 | 0.86 | IRAK4 (0.35) | KMT2APOLBMEN1ALDH1A1GABRA1 | |
| SCHEMBL16956824 | 0.83 | ALDH1A1 (0.39) | KMT2AHTTPOLBSMN1; SMN2DRD1 | |
| SCHEMBL16953280 | 0.83 | KMT2A (0.35) | KMT2AHTTPOLBSMN1; SMN2DRD1 | |
| SCHEMBL16955100 | 0.82 | POLB (0.40) | HTTPOLBSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL16958070 | 0.81 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL16961269 | 0.80 | MEN1 (0.35) | KMT2AHTTSLC6A2SLC6A4KCNH2 | |
| SCHEMBL16951529 | 0.80 | DRD1 (0.33) | KMT2ADRD1MEN1TSHRRAB9A | |
| SCHEMBL16953507 | 0.79 | MPL (0.37) | SLC6A2SLC6A4KCNH2 | |
| SCHEMBL16961924 | 0.78 | KMT2A (0.38) | KMT2AHTTPOLBSMN1; SMN2SLC6A2 | |
| SCHEMBL16961608 | 0.77 | HTT (0.33) | KMT2AHTTSMN1; SMN2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |