Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.31 |
| ▸ | PDE4A | P27815 | 4/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954024 | 0.86 | KCNH2 (0.36) | KMT2ASLC6A4KCNH2NTRK1MAPT | |
| SCHEMBL16953498 | 0.83 | HPGD (0.34) | HTTSMN1; SMN2PDE4BPDE4APDE4C | |
| SCHEMBL16958907 | 0.83 | KMT2A (0.40) | HTTPDE4AKMT2ALMNAALDH1A1 | |
| SCHEMBL16953760 | 0.82 | ADRA2A (0.38) | SMN1; SMN2SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL16961984 | 0.81 | L3MBTL1 (0.38) | SMN1; SMN2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL16954586 | 0.80 | ALDH1A1 (0.34) | HTTSMN1; SMN2PDE4BPDE4APDE4C | |
| SCHEMBL16951360 | 0.79 | PDE2A (0.35) | SLC6A2SLC6A4SLC6A3KCNH2SCN9A | |
| SCHEMBL16956920 | 0.78 | HTR2A (0.37) | HTTSMN1; SMN2PDE4BKMT2ASLC6A4 | |
| SCHEMBL16950475 | 0.77 | KMT2A (0.34) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL16952073 | 0.77 | MAPT (0.44) | HTTSMN1; SMN2PDE4BKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |