Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 14/20 | 0.43 |
| ▸ | CNR2 | P34972 | 11/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960689 | 0.91 | PTGS2 (0.43) | PTGS2CNR1CNR2CALM1AKR1B1 | |
| SCHEMBL16955074 | 0.87 | CNR2 (0.42) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16958376 | 0.86 | HPGD (0.44) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16952839 | 0.85 | PTGS2 (0.48) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16952594 | 0.85 | CNR2 (0.36) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16956693 | 0.84 | PTGS2 (0.35) | PTGS2CNR1CNR2MAPK1CALM1 | |
| SCHEMBL16959399 | 0.83 | ALOX5 (0.40) | PTGS2CNR1CNR2 | |
| SCHEMBL16954178 | 0.83 | CNR1 (0.35) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16954486 | 0.83 | PTGS2 (0.51) | PTGS2CNR1CNR2NPC1HPGD | |
| SCHEMBL16961458 | 0.83 | NPC1 (0.42) | PTGS2CNR1CNR2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |