Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767842 | 0.85 | TDP1 (0.67) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL27576224 | 0.83 | ALDH1A1 (0.53) | TDP1TSHRSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL992241 | 0.83 | ALDH1A1 (0.53) | TDP1TSHRSMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL16961100 | 0.83 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL24440376 | 0.82 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL16971066 | 0.82 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL6676584 | 0.82 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL29238525 | 0.82 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| Hydrochloric Acid SCHEMBL29238521 | 0.81 | TDP1 (0.60) | TDP1TSHRSMN1; SMN2GLAHSD17B10 | |
| SCHEMBL27582724 | 0.81 | TDP1 (0.60) | TDP1TSHRSMN1; SMN2GLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |