Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175919 | 0.89 | XDH (0.50) | XDHGAATSHRNR1H4CA12 | |
| SCHEMBL2177328 | 0.83 | NR1H4 (0.50) | XDHGAATSHRNR1H4CA12 | |
| SCHEMBL2650533 | 0.83 | CA12 (0.58) | XDHGAATSHRNR1H4CA12 | |
| SCHEMBL16957370 | 0.83 | KDM4E (0.44) | XDHGAATSHRCA12CA1 | |
| SCHEMBL16961131 | 0.81 | GAA (0.43) | XDHGAATSHRNR1H4MAPT | |
| SCHEMBL10068564 | 0.81 | XDH (0.44) | XDHGAATSHRNR1H4CA12 | |
| SCHEMBL10068560 | 0.79 | ALDH1A1 (0.45) | XDHGAATSHRNR1H4CA12 | |
| SCHEMBL16962165 | 0.79 | MAPT (0.50) | TSHRMAPTKDM4EL3MBTL1SMPD1 | |
| SCHEMBL16957757 | 0.79 | CA1 (0.52) | XDHGAATSHRCA12CA1 | |
| SCHEMBL26049008 | 0.77 | NR1H4 (0.60) | XDHTSHRNR1H4HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |