Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654599 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL10176626 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL446475 | 0.79 | TDP1 (0.55) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL30279254 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL4641866 | 0.78 | HSD17B10 (0.60) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL11997404 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL2031510 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL395055 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL397097 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 | |
| SCHEMBL395023 | 0.78 | TSHR (0.59) | SMN1; SMN2HTTL3MBTL1MEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |