Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17704246 | 0.85 | TDP1 (0.52) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL3656487 | 0.85 | TDP1 (0.52) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL11654599 | 0.84 | SMN1; SMN2 (0.60) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL9505333 | 0.84 | TDP1 (0.50) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL18925062 | 0.82 | TDP1 (0.49) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL11833322 | 0.81 | TDP1 (0.50) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL8147133 | 0.81 | ALDH1A1 (0.58) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL13945797 | 0.81 | ALDH1A1 (0.50) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL4747577 | 0.81 | TDP1 (0.55) | TDP1ALDH1A1SMN1; SMN2MAPK1GPR35 | |
| SCHEMBL12737451 | 0.81 | TSHR (0.62) | TDP1ALDH1A1SMN1; SMN2GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574001-A | Preparation method of m-tert-butylphenol | 南通书创药业科技有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-1679521-A | Use of substituting nitrobenzene derivative in products preparation | MEN TEWA (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-1193746-C | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | NEN TEWA (CN) | 2005-03-23 | — | — | CN | claimed |
| CN-1294911-A | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | MEN TEWA (CN) | 2001-05-16 | — | — | CN | claimed |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-06-22 | — | — | US | disclosed |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-05-04 | — | — | US | disclosed |
| CN-112574001-A | Preparation method of m-tert-butylphenol | 南通书创药业科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112574001-A | Preparation method of m-tert-butylphenol | 南通书创药业科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2021-01-14 | — | — | US | disclosed |
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2020-01-30 | — | — | US | disclosed |
| US-20180224577-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) | 2018-08-09 | — | — | US | disclosed |
| US-9977150-B2 | Second-order nonlinear optical compound and nonlinear optical element comprising the same | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) | 2018-05-22 | — | — | US | disclosed |
| CN-1294911-A | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | MEN TEWA (CN) | 2001-05-16 | — | — | CN | disclosed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| US-4992527-A | Heat resistance, protective coatings, electronics | AMOCO CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4973659-A | HEAR RESISTANT FILMS, FIBERS, COMPOSITES | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| US-4973660-A | Polyamide of diamino-t-butyltoluene | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| US-4968780-A | SOLUBLE IN N-METHYLPYRROLIDONE, HIGH GLASS TRANSITION TEMPERATURE, HEAT RESISTANT FILMS, FIBERS AND COMPOSITES | AMOCO CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| US-4963648-A | SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | FURIN, PEPD, PIN1 | TDP1 3073/4885ALDH1A1 4014/4885SMN1; SMN2 1122/4885 |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | FURIN, PEPD, PIN1 | TDP1 3073/4885ALDH1A1 4014/4885SMN1; SMN2 1122/4885 |
| US-20180224577-A1 | SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME | OGFOD1, OCIAD2, OCIAD1 | TDP1 3636/4885ALDH1A1 1660/4885SMN1; SMN2 1968/4885 |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | TPMT, MAPT, TLR4 | TDP1 1592/4885ALDH1A1 1738/4885SMN1; SMN2 2503/4885 |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | TPMT, PBRM1, PGM2 | TDP1 1723/4885ALDH1A1 1622/4885SMN1; SMN2 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.