Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238859 | 0.83 | ACHE (0.58) | ACHEALDH1A1CYP3A4CYP2D6LPAR1 | |
| SCHEMBL29591727 | 0.83 | ACHE (0.58) | ACHEALDH1A1CYP3A4CYP2D6LPAR1 | |
| SCHEMBL16950714 | 0.82 | ACHE (0.38) | ACHEALDH1A1CYP3A4GAAMAPT | |
| SCHEMBL16956906 | 0.81 | ACHE (0.50) | ACHEALDH1A1CYP3A4CYP2D6LPAR1 | |
| SCHEMBL16956296 | 0.81 | MAPT (0.44) | ACHEALDH1A1GAATDP1MAPT | |
| SCHEMBL12476289 | 0.80 | ACHE (0.54) | ACHEALDH1A1CYP3A4CYP2D6LPAR1 | |
| SCHEMBL18793769 | 0.80 | ACHE (0.54) | ACHEALDH1A1CYP3A4CYP2D6LPAR1 | |
| SCHEMBL11260013 | 0.80 | CYP2D6 (0.62) | ACHEALDH1A1CYP2D6GAAMAPT | |
| SCHEMBL16954278 | 0.79 | ALDH1A1 (0.44) | ACHEALDH1A1CYP3A4GAAMAPT | |
| SCHEMBL16951333 | 0.78 | LPAR1 (0.41) | ALDH1A1CYP2D6LPAR1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |