Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993148 | 0.73 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL22698222 | 0.71 | MLYCD (0.32) | MLYCD | |
| SCHEMBL402583 | 0.69 | — | — | |
| SCHEMBL22861185 | 0.68 | S1PR1 (0.33) | MAPK14 | |
| SCHEMBL14227844 | 0.68 | MAPK14 (0.30) | MAPK14 | |
| Hydrochloric Acid SCHEMBL28751278 | 0.67 | — | — | |
| SCHEMBL12000463 | 0.67 | — | — | |
| SCHEMBL24191100 | 0.67 | BRD4 (0.39) | BRD4TDO2 | |
| SCHEMBL19102117 | 0.67 | MLYCD (0.32) | MLYCD | |
| SCHEMBL21191286 | 0.66 | RET (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889978-B | PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS | 霍夫曼-拉罗奇有限公司 | 2017-02-15 | — | — | CN | disclosed |
| EP-2588467-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | Amgen Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003274-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | AMGEN INC. (US) | 2012-01-05 | — | — | WO | disclosed |