Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950664 | 0.88 | PPARG (0.41) | CYP3A4TSHRPPARGPPARDPPARA | |
| SCHEMBL16962465 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2HTR2A | |
| SCHEMBL16951872 | 0.81 | HIF1A (0.41) | HIF1AHTR2CHTR2ADRD2 | |
| SCHEMBL16959971 | 0.80 | OPRL1 (0.35) | HTR2C | |
| SCHEMBL16953953 | 0.79 | PPARG (0.62) | CYP3A4TSHRPPARGPPARDPPARA | |
| SCHEMBL16952484 | 0.79 | HTR2C (0.37) | PPARGPPARDPPARAHIF1AHTR2C | |
| SCHEMBL27016299 | 0.78 | HDAC4 (0.46) | HIF1AHTR2CHTR2ADRD2 | |
| SCHEMBL16956893 | 0.77 | LMNA (0.36) | CYP3A4SMN1; SMN2HTR2CHTR2A | |
| SCHEMBL16960948 | 0.77 | SLC6A2 (0.38) | — | |
| SCHEMBL16953481 | 0.77 | PDE2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |