Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956893 | 0.89 | LMNA (0.36) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL16951548 | 0.86 | CYP3A4 (0.41) | SMN1; SMN2HTR2A | |
| SCHEMBL16957023 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAHTTHTR6CNR2 | |
| SCHEMBL16961314 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNAHTTHTR6CNR2 | |
| SCHEMBL16954484 | 0.78 | ACHE (0.46) | SMN1; SMN2LMNAHTTALDH1A1GAA | |
| SCHEMBL16959971 | 0.78 | OPRL1 (0.35) | HTR6 | |
| SCHEMBL16956733 | 0.77 | HTR2A (0.35) | PROKR1ALDH1A1MAPTHTR2AAPOBEC3G | |
| SCHEMBL16950664 | 0.77 | PPARG (0.41) | SMN1; SMN2HTR2A | |
| SCHEMBL16955262 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2LMNAHTTALDH1A1GAA | |
| SCHEMBL16957241 | 0.77 | PPARG (0.50) | SMN1; SMN2LMNAALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |