Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955654 | 0.83 | HTR2C (0.41) | ERN1PTGDR2MEN1KMT2AHTR2C | |
| SCHEMBL16957548 | 0.82 | CHRNB2 (0.41) | CHRNB2CHRNA4POLBRAB9AALDH1A1 | |
| SCHEMBL16960068 | 0.79 | TRPV1 (0.40) | NFKB1CYP1A2NPC1RAB9A | |
| SCHEMBL30888638 | 0.77 | PTGDR2 (0.45) | PTGDR2MEN1KMT2AHTR2CCYP1A1 | |
| SCHEMBL16957024 | 0.77 | CHRNB2 (0.38) | PTGDR2HTR2CCHRNB2CHRNA4NOS3 | |
| SCHEMBL23268487 | 0.74 | MEN1 (0.58) | PTGDR2MEN1KMT2AHTR2CCYP1A1 | |
| SCHEMBL31172738 | 0.74 | MEN1 (0.58) | PTGDR2MEN1KMT2AHTR2CCYP1A1 | |
| SCHEMBL16954478 | 0.74 | ESR2 (0.39) | HTR2C | |
| SCHEMBL6872023 | 0.74 | PROKR1 (0.44) | PTGDR2MEN1KMT2AHTR2CCHRNB2 | |
| SCHEMBL3692141 | 0.74 | MEN1 (0.58) | PTGDR2MEN1KMT2AHTR2CCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |