Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955210 | 0.84 | TRPV1 (0.40) | TRPV1GPR3NOTUMPPARDPPARA | |
| SCHEMBL22208778 | 0.79 | FFAR4 (0.40) | TRPV1GPR3NOTUMDHODHCCNA2 | |
| SCHEMBL16951580 | 0.79 | ERN1 (0.42) | NPC1RAB9ACYP1A2NFKB1 | |
| SCHEMBL16961113 | 0.76 | HTR1A (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL16960456 | 0.76 | CHRNB2 (0.44) | — | |
| SCHEMBL16954439 | 0.76 | GPR3 (0.40) | TRPV1GPR3NOTUMPPARDPPARA | |
| SCHEMBL16954442 | 0.76 | TRPV1 (0.42) | TRPV1GPR3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25212456 | 0.75 | FFAR4 (0.42) | TRPV1GPR3NOTUMPPARDPPARA | |
| SCHEMBL16957548 | 0.75 | CHRNB2 (0.41) | PPARDCYP3A4RAB9ATP53SLC6A2 | |
| SCHEMBL16955208 | 0.75 | TRPV1 (0.37) | TRPV1GPR3NOTUMPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |