Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959816 | 0.88 | MAPT (0.46) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL11890402 | 0.85 | GAA (0.52) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16951022 | 0.83 | GAA (0.51) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16951333 | 0.81 | LPAR1 (0.41) | GAAHPGDCYP2D6MAPTMEN1 | |
| SCHEMBL16959581 | 0.81 | GAA (0.47) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16960393 | 0.81 | TSHR (0.48) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16956296 | 0.80 | MAPT (0.44) | GAATSHRHPGDMAPTMEN1 | |
| SCHEMBL16953753 | 0.80 | CSNK2A1 (0.41) | TSHRMAPTHTR2CHTR2BHTR2A | |
| SCHEMBL16961368 | 0.79 | TSHR (0.47) | GAATSHRHPGDMAPTMEN1 | |
| SCHEMBL16962099 | 0.79 | L3MBTL1 (0.41) | GAACYP1A2CYP2D6MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |