Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958642 | 0.89 | MAPT (0.43) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16958455 | 0.85 | MEN1 (0.40) | MEN1KMT2AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL16960393 | 0.84 | TSHR (0.48) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16956882 | 0.82 | MAPT (0.41) | GAATSHRHPGDATMMEN1 | |
| SCHEMBL16960641 | 0.82 | L3MBTL1 (0.39) | GAACYP1A2CYP2D6MAPTNPSR1 | |
| SCHEMBL16951644 | 0.81 | GAA (0.50) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16953417 | 0.81 | TSHR (0.44) | GAATSHRHPGDMEN1KMT2A | |
| SCHEMBL16951022 | 0.79 | GAA (0.51) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL11890402 | 0.78 | GAA (0.52) | GAATSHRHPGDCYP1A2CYP2D6 | |
| SCHEMBL16954699 | 0.77 | TRPV4 (0.46) | GAAHPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |