Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956284 | 0.80 | ALDH1A1 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16958974 | 0.78 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL16957617 | 0.78 | MEN1 (0.33) | NPC1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL16950693 | 0.78 | GABRA1 (0.41) | MAPTALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL16958238 | 0.77 | ALDH1A1 (0.33) | ALDH1A1GAAKMT2AHTT | |
| SCHEMBL16956014 | 0.77 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL16959460 | 0.77 | KMT2A (0.36) | MAPTSMN1; SMN2ALDH1A1GAAMAPK1 | |
| SCHEMBL16953025 | 0.77 | ALDH1A1 (0.33) | MAPTRAB9AALDH1A1GAAKMT2A | |
| SCHEMBL16954519 | 0.77 | KIT (0.31) | — | |
| SCHEMBL16956070 | 0.77 | MAPT (0.37) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |