Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.64 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696553 | 0.86 | GABRA1 (0.61) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL16955749 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL16953307 | 0.83 | GABRA1 (0.41) | GABRA1GABRB2LMNANPC1RAB9A | |
| SCHEMBL16952873 | 0.82 | GABRA1 (0.57) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL936645 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL16951114 | 0.81 | GABRA1 (0.55) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL27598816 | 0.80 | GABRA1 (0.59) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL28204006 | 0.80 | GABRA1 (0.59) | GABRA1GABRB2CLCN2ALDH1A1LMNA | |
| SCHEMBL16954541 | 0.80 | GABRA1 (0.53) | GABRA1GABRB2CLCN2HTTF2R | |
| SCHEMBL62557 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2DAOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |