Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.55 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951825 | 0.86 | GABRA1 (0.38) | GABRA1GABRB2HTTBCHELMNA | |
| SCHEMBL16952873 | 0.84 | GABRA1 (0.57) | GABRA1GABRB2CLCN2HTTKAT6A | |
| SCHEMBL16958341 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2CLCN2HTTKAT6A | |
| SCHEMBL16959503 | 0.81 | KAT6A (0.46) | GABRA1GABRB2CLCN2HTTKAT6A | |
| SCHEMBL16951723 | 0.81 | GABRA1 (0.64) | GABRA1GABRB2CLCN2HTTKAT6A | |
| SCHEMBL16952951 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2CLCN2HTTKAT6A | |
| SCHEMBL16961076 | 0.79 | KMT2A (0.37) | GABRA1GABRB2HTTKAT6ABCHE | |
| SCHEMBL5696553 | 0.79 | GABRA1 (0.61) | GABRA1GABRB2CLCN2HTTALDH1A1 | |
| SCHEMBL16955031 | 0.79 | ALDH1A1 (0.32) | GABRA1GABRB2HTTALDH1A1LMNA | |
| SCHEMBL16951272 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2CLCN2HTTKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |