Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447680 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL8843838 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| Hydrochloric Acid SCHEMBL8556297 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL5272375 | 0.81 | HIF1A (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL5272379 | 0.81 | HIF1A (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL8578234 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1ASLC6A2TAAR1TSHR | |
| SCHEMBL7514054 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL410219 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL410218 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 | |
| SCHEMBL28095334 | 0.75 | ARG1 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072933-A2 | PROCESS FOR PREPARATION OF 2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE | GLENMARK GENERICS LIMITED (IN) | 2013-05-23 | — | — | WO | claimed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | claimed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | claimed |
| EP-2914574-A2 | NEW PROCESS | Cambrex Karlskoga Ab (SE) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068333-A2 | NEW PROCESS | CAMBREX KARLSKOGA AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| WO-2013072933-A2 | PROCESS FOR PREPARATION OF 2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE | GLENMARK GENERICS LIMITED (IN) | 2013-05-23 | — | — | WO | disclosed |
| EP-2582833-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | Medichem, S.A. (ES) | 2013-04-24 | — | — | EP | disclosed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011158194-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | MEDICHEM, S.A. (ES) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | disclosed |
| WO-2000000463-A1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-01-06 | — | — | WO | disclosed |