Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953513 | 0.88 | MAPT (0.44) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16951261 | 0.84 | LMNA (0.37) | CFDLMNAKDM4EMAPTCYP3A4 | |
| SCHEMBL16957004 | 0.83 | CYP19A1 (0.38) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16955690 | 0.83 | CYP4F2 (0.39) | CFDLMNAKDM4EMAPTCYP3A4 | |
| SCHEMBL16959879 | 0.81 | CYP4F2 (0.38) | CFDLMNAKDM4EMAPTCYP3A4 | |
| SCHEMBL16954601 | 0.81 | KMT2A (0.45) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16957884 | 0.81 | LMNA (0.47) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16953316 | 0.80 | LMNA (0.39) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16950576 | 0.80 | LMNA (0.36) | LMNAKDM4EMAPTCYP3A4TP53 | |
| SCHEMBL16956152 | 0.80 | BACE1 (0.38) | LMNAKDM4EMAPTCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |