Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959876 | 0.89 | CYP4F2 (0.44) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16959879 | 0.87 | CYP4F2 (0.38) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16955371 | 0.83 | BACE1 (0.40) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16950752 | 0.83 | CYP4F2 (0.40) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16953473 | 0.83 | LMNA (0.44) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16961476 | 0.83 | CYP4F2 (0.40) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16952032 | 0.83 | CFD (0.37) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16951009 | 0.82 | CYP4F2 (0.39) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16956220 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16961677 | 0.81 | ABCB11 (0.36) | CYP3A4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |