Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960034 | 0.86 | NQO1 (0.36) | ACACB | |
| SCHEMBL16958654 | 0.84 | LTA4H (0.42) | CYP1A2KDM4ECYP2D6PDE4ASMN1; SMN2 | |
| SCHEMBL13261657 | 0.84 | PTGES (0.46) | PTGESALOX5PPARGCYP1A2KDM4E | |
| SCHEMBL16956038 | 0.83 | CNR1 (0.40) | SMN1; SMN2LTA4HNR5A1GAARAB9A | |
| SCHEMBL16954681 | 0.83 | CNR1 (0.40) | CYP2D6SMN1; SMN2LTA4HNR5A1GAA | |
| SCHEMBL16953683 | 0.83 | ACACB (0.35) | ACACBKDM4ECYP2D6SMN1; SMN2RAB9A | |
| SCHEMBL16960766 | 0.80 | PTGES (0.39) | ACACBPTGESALOX5PPARGCYP1A2 | |
| SCHEMBL16951174 | 0.80 | TAAR1 (0.38) | CYP19A1 | |
| SCHEMBL16951561 | 0.79 | HTT (0.42) | PTGESALOX5PPARGKDM4ELTA4H | |
| SCHEMBL16953810 | 0.79 | CNR1 (0.40) | PTGESALOX5PPARGKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |