Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1694763 | 0.98 | MAPK1 (0.44) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL22470860 | 0.85 | ALDH1A1 (0.41) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL17584937 | 0.81 | KDM4E (0.50) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL16493428 | 0.80 | KDM4E (0.42) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL2594097 | 0.80 | KDM4E (0.46) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL10749671 | 0.79 | KDM4E (0.49) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL21489626 | 0.79 | KDM4E (0.41) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL1695049 | 0.79 | PARP1 (0.42) | KDM4EPKMALDH1A1EZH2PARP1 | |
| Hydrochloric Acid SCHEMBL2591197 | 0.79 | KDM4E (0.45) | MAPK1KDM4EPKMALDH1A1KMT2A | |
| SCHEMBL21489621 | 0.77 | KDM4E (0.40) | MAPK1KDM4EPKMGAAEZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 667 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406041-A | Tazemetostat synthesis method | 沈阳药科大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118388399-A | N- ((4, 6-dimethyl-2-oxo-1, 2-dihydropyridine-3-yl) methyl) benzamide compound and preparation method and application thereof | 承德医学院 | 2024-07-26 | — | — | CN | claimed |
| CN-118222101-A | Hydrogen bond enhanced graphene composite shape memory polymer and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-06-21 | — | — | CN | claimed |
| CN-118055928-A | Preparation method of benzofuran derivative | 江苏恒瑞医药股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117069696-B | Double-target small molecule inhibitor and preparation method and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116768857-A | EZH2/HDAC double-target inhibitor and preparation method and medical application thereof | 中国药科大学 | 2023-09-19 | — | — | CN | claimed |
| CN-116655612-A | Synthetic method and application of EZH2 inhibitor | 王亚男 | 2023-08-29 | — | — | CN | claimed |
| CN-116655619-A | 2H-indazole compound and preparation method and application thereof | 南京康立凯医药科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| US-20230257368-A1 | METHOD FOR PRODUCING 1,3-BENZODIOXOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-08-17 | — | — | US | claimed |
| CN-111094279-B | Preparation method of benzofuran derivative | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | claimed |
| EP-4180426-A1 | METHOD FOR PRODUCING 1,3-BENZODIOXOLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2023-05-17 | — | — | EP | claimed |
| CN-116018335-A | Process for preparing 1, 3-benzodioxole derivatives | 第一三共株式会社 | 2023-04-25 | — | — | CN | claimed |
| CN-114409636-B | Quinazolinone compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 沈阳药科大学 | 2023-04-18 | — | — | CN | claimed |
| CN-113767096-B | Preparation method of 6-substituted aminobenzofuran compound | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-114456156-A | Purification method of 6-substituted aminobenzofuran compound | 江苏恒瑞医药股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-113767096-A | Preparation method of 6-substituted aminobenzofuran compound | 江苏恒瑞医药股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-111094279-A | Preparation method of benzofuran derivative | 江苏恒瑞医药股份有限公司 | 2020-05-01 | — | — | CN | claimed |
| EP-4709721-A1 | DUAL EZH2-HSP90 INHIBITORS | Taipei Medical University (TW) | 2026-03-18 | — | — | EP | disclosed |
| WO-2011140325-A1 | INDAZOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011140325-A1 | INDAZOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257368-A1 | METHOD FOR PRODUCING 1,3-BENZODIOXOLE DERIVATIVE | BBOX1, CBR3, CBR1 | MAPK1 4251/4885KDM4E 2453/4885PKM 4066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.