Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952555 | 0.86 | KDM4E (0.40) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL16951242 | 0.84 | KDM4E (0.38) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL31225154 | 0.82 | ALDH1A1 (0.45) | KDM4ECHRNB2CHRNA4PPARDABL1 | |
| SCHEMBL16957894 | 0.81 | PTGDR2 (0.40) | KDM4ECHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL16957262 | 0.78 | NQO1 (0.45) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL16957550 | 0.77 | CHRNB2 (0.42) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL31225273 | 0.77 | CHRNB2 (0.42) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL16957258 | 0.77 | CHRNB2 (0.43) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL15716233 | 0.76 | ALDH1A1 (0.46) | KDM4ECHRNB2CHRNA4NQO1PPARD | |
| SCHEMBL16957548 | 0.76 | CHRNB2 (0.41) | KDM4ECHRNB2CHRNA4NQO1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |