Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955812 | 0.85 | F2R (0.34) | CA12 | |
| SCHEMBL16954470 | 0.81 | TLR2 (0.44) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL16956543 | 0.79 | ALDH1A1 (0.40) | KDM4E | |
| SCHEMBL16955698 | 0.78 | GSK3A (0.38) | FBP1KDM4E | |
| SCHEMBL16953870 | 0.77 | TLR2 (0.37) | KCNH2CA12TLR2ERN1TLR1 | |
| SCHEMBL16957355 | 0.77 | KCNH2 (0.35) | KCNH2CA12TLR2ERN1TLR1 | |
| SCHEMBL16962844 | 0.77 | MCHR1 (0.39) | KDM4E | |
| SCHEMBL16962240 | 0.77 | KCNH2 (0.33) | KCNH2TLR2ERN1TLR1TLR6 | |
| SCHEMBL16962569 | 0.77 | CA1 (0.39) | KDM4EGABRA1GABRB2 | |
| SCHEMBL16951759 | 0.76 | APP (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |