Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953545 | 0.88 | GSK3A (0.38) | GSK3AMAPTATML3MBTL1MEN1 | |
| SCHEMBL16960196 | 0.85 | MEN1 (0.42) | GSK3AMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL16953072 | 0.82 | GSK3A (0.52) | GSK3AMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL16957104 | 0.82 | NFE2L2 (0.45) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL16952225 | 0.81 | NFE2L2 (0.33) | LMNAL3MBTL1ALDH1A1GAA | |
| SCHEMBL16950721 | 0.79 | PTGES (0.41) | GSK3AMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL16955079 | 0.79 | GSK3A (0.36) | GSK3AMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL16955265 | 0.78 | GSK3A (0.38) | GSK3AMAPTLMNAATMMEN1 | |
| SCHEMBL16954498 | 0.78 | PDK2 (0.40) | MAPTLMNAATMSMN1; SMN2L3MBTL1 | |
| SCHEMBL16952532 | 0.78 | KCNH2 (0.33) | KDM4EFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |