SCHEMBL16952633

SCHEMBL16952633

[CH2]C(CO)c1cccc(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.53
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MTNR1A P48039 2/20 0.49
MTNR1B P49286 2/20 0.49
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
CASR P41180 2/20 0.46
ABCB11 O95342 1/20 0.45
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3080355 0.83 AOC3 (0.50) AOC3L3MBTL1MTNR1AMTNR1BCHRM2
SCHEMBL8661020 0.83 AOC3 (0.54) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL16952488 0.82 ALDH1A1 (0.46) AOC3TSHRMAPK1ABCB11
SCHEMBL16955329 0.82 TP53 (0.49) TSHRMAPK1L3MBTL1
SCHEMBL24925773 0.81 ABCB11 (0.67) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL6492140 0.81 AOC3 (0.66) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL16419134 0.81 AOC3 (0.66) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL20738720 0.81 ABCB11 (0.67) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL22785842 0.81 AOC3 (0.66) AOC3TSHRMAPK1L3MBTL1MTNR1A
SCHEMBL30988794 0.81 AOC3 (0.66) AOC3TSHRMAPK1L3MBTL1MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed