Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952725 | 0.85 | SMN1; SMN2 (0.40) | TSHRCA1CA2SMN1; SMN2HIF1A | |
| SCHEMBL16959168 | 0.83 | ALDH1A1 (0.32) | TSHRSMN1; SMN2HIF1AKDM4EALDH1A1 | |
| SCHEMBL3208689 | 0.79 | TSHR (0.35) | TSHRCA1CA2SMN1; SMN2HIF1A | |
| SCHEMBL16961790 | 0.77 | CYP1A2 (0.33) | TSHRKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16953718 | 0.75 | ALDH1A1 (0.33) | TSHRCA1CA2SMN1; SMN2HIF1A | |
| SCHEMBL18297484 | 0.75 | KDM4E (0.38) | TSHRCA1CA2SMN1; SMN2HIF1A | |
| SCHEMBL16956053 | 0.75 | TSHR (0.35) | TSHRCA1CA2ALDH1A1 | |
| SCHEMBL16956043 | 0.75 | — | — | |
| SCHEMBL16956411 | 0.75 | — | — | |
| SCHEMBL16956590 | 0.75 | L3MBTL1 (0.30) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |