Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961272 | 0.86 | GPR35 (0.42) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16955121 | 0.83 | TDP1 (0.40) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16958845 | 0.83 | TDP1 (0.55) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16951443 | 0.83 | TDP1 (0.39) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16962730 | 0.80 | TDP1 (0.40) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16951095 | 0.80 | TDP1 (0.37) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16951733 | 0.80 | TDP1 (0.46) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16959043 | 0.79 | ALDH1A1 (0.39) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16960997 | 0.79 | TDP1 (0.41) | TDP1GPR35TSHRCYP1A2ALDH1A1 | |
| SCHEMBL16955345 | 0.79 | TDP1 (0.41) | TDP1GPR35TSHRCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |