Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769710 | 0.80 | KIF11 (0.47) | APPTAS2R14ALKBH5NOTUMS1PR1 | |
| SCHEMBL16957018 | 0.80 | TP53 (0.41) | APPTAS2R14ALKBH5NOTUMS1PR1 | |
| SCHEMBL16952265 | 0.78 | PTGS1 (0.42) | APPNPFFR1NPFFR2PTGS1PTGS2 | |
| SCHEMBL16950767 | 0.76 | APP (0.40) | APPNOTUMNPFFR1NPFFR2PTGS1 | |
| SCHEMBL16952200 | 0.76 | NPFFR2 (0.57) | APPNOTUMNPFFR1NPFFR2 | |
| SCHEMBL16958704 | 0.76 | MAPT (0.41) | APPTAS2R14ALKBH5NOTUMNPFFR1 | |
| SCHEMBL16958461 | 0.76 | APP (0.41) | APP | |
| SCHEMBL16952295 | 0.76 | NOTUM (0.40) | APPNOTUMS1PR1NPFFR1NPFFR2 | |
| SCHEMBL6632434 | 0.73 | TUBB1 (0.46) | PTGS1PTGS2 | |
| SCHEMBL16957249 | 0.73 | APP (0.36) | APPS1PR1NPFFR1NPFFR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |