Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.57 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46855 | 0.82 | NPFFR2 (0.54) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL9996968 | 0.80 | NPFFR1 (0.53) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL9996969 | 0.80 | NPFFR2 (0.53) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL40676 | 0.80 | ALDH1A1 (0.57) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL1720610 | 0.79 | NPFFR2 (0.53) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL15611218 | 0.79 | NPFFR2 (0.65) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL15611217 | 0.79 | NPFFR2 (0.65) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL2096625 | 0.77 | NPFFR2 (0.50) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL2096623 | 0.77 | NPFFR2 (0.50) | NPFFR2NPFFR1KDRHTR3EHTR3B | |
| SCHEMBL16953201 | 0.76 | APP (0.40) | NPFFR2NPFFR1NOTUMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |