SCHEMBL16953239

SCHEMBL16953239

CCCCOc1cc(CO)cc(CCC)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.46
CNR2 P34972 12/20 0.46
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SLCO1B3 Q9NPD5 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
LTA4H P09960 1/20 0.41
NR5A1 Q13285 1/20 0.41
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16958517 0.93 CNR1 (0.49) CNR1CNR2MEN1USP2ALDH1A1
SCHEMBL2771611 0.93 LTA4H (0.46) CNR1CNR2MEN1USP2ALDH1A1
SCHEMBL13016545 0.89 PLA2G2A (0.49) CNR1CNR2MEN1USP2ALDH1A1
SCHEMBL16960275 0.87 LTA4H (0.46) CNR1CNR2MEN1USP2ALDH1A1
SCHEMBL17407555 0.87 PLA2G2A (0.51) CNR1CNR2LTA4HNR5A1PLA2G2A
SCHEMBL31406533 0.86 CNR1 (0.60) CNR1CNR2
SCHEMBL5488935 0.85 PLA2G2A (0.54) CNR1CNR2NR5A1PLA2G2A
SCHEMBL5486708 0.85 PLA2G2A (0.54) CNR1CNR2NR5A1PLA2G2A
SCHEMBL2711668 0.85 PLA2G2A (0.54) CNR1CNR2NR5A1PLA2G2A
SCHEMBL2712563 0.85 PLA2G2A (0.54) CNR1CNR2NR5A1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed