Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954501 | 0.88 | ALDH1A1 (0.40) | HCRTR1HCRTR2ALDH1A1PDK2KMT2A | |
| SCHEMBL16951131 | 0.85 | GRIN2B (0.38) | PDK2KMT2AVNN1MAPTMEN1 | |
| SCHEMBL16950764 | 0.84 | GRIN2B (0.40) | HCRTR1HCRTR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7669246 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL16955081 | 0.83 | KMT2A (0.38) | HCRTR1HCRTR2ALDH1A1PDK2KMT2A | |
| SCHEMBL1254447 | 0.82 | MCL1 (0.41) | HCRTR1HCRTR2ALDH1A1PPARGEPHX2 | |
| SCHEMBL1254450 | 0.82 | TAAR1 (0.42) | HCRTR1HCRTR2SLC6A3SLC6A2DRD2 | |
| SCHEMBL16953073 | 0.80 | KMT2A (0.51) | ALDH1A1KMT2AL3MBTL1HPGD | |
| SCHEMBL16957328 | 0.79 | CYP4F2 (0.42) | ALDH1A1KMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL16961972 | 0.79 | CHRM2 (0.36) | HCRTR1HCRTR2PPARGVNN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |