Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961972 | 0.88 | CHRM2 (0.36) | HCRTR1HCRTR2L3MBTL1MAPTNPSR1 | |
| SCHEMBL16953547 | 0.88 | HCRTR1 (0.40) | ALDH1A1HCRTR1HCRTR2PDK2L3MBTL1 | |
| SCHEMBL16951131 | 0.85 | GRIN2B (0.38) | PDK2MAPTKMT2AMEN1SLC6A2 | |
| SCHEMBL16950633 | 0.84 | GRIN2B (0.43) | ALDH1A1HCRTR1HCRTR2L3MBTL1MAPT | |
| SCHEMBL7669246 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL2353503 | 0.80 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL16955333 | 0.80 | GABRA1 (0.45) | PDK2MAPTKMT2AMEN1SLC6A2 | |
| SCHEMBL16955081 | 0.80 | KMT2A (0.38) | ALDH1A1HCRTR1HCRTR2PDK2L3MBTL1 | |
| SCHEMBL16957013 | 0.80 | KCNK3 (0.43) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16955205 | 0.79 | SCN8A (0.42) | ALDH1A1HCRTR1HCRTR2PDK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |