Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951448 | 0.81 | LMNA (0.33) | CYP1A2CYP2D6CYP2C19TDP1KDM4E | |
| SCHEMBL16955715 | 0.81 | HSP90AA1 (0.34) | TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL16957153 | 0.79 | NPC1 (0.33) | CYP1A2MAPTLMNA | |
| SCHEMBL16957412 | 0.79 | PKM (0.31) | — | |
| SCHEMBL16950424 | 0.78 | ALKBH3 (0.35) | CYP2C19ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL16953998 | 0.78 | — | — | |
| SCHEMBL16953786 | 0.78 | MAPT (0.31) | MAPT | |
| SCHEMBL16952366 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL16950494 | 0.76 | LMNA (0.38) | CYP1A2TDP1ALDH1A1MAPTHPGD | |
| SCHEMBL16959677 | 0.76 | NQO1 (0.41) | CYP1A2TDP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |