Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956842 | 0.86 | MAPT (0.40) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16957056 | 0.83 | MEN1 (0.37) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16954235 | 0.83 | MAPT (0.40) | MAPTALDH1A1 | |
| SCHEMBL16956610 | 0.83 | HPGD (0.40) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16957061 | 0.80 | MAOB (0.36) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16953386 | 0.80 | F2 (0.35) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16956671 | 0.80 | MAPT (0.35) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16951966 | 0.80 | PDE4A (0.38) | MAPTALDH1A1 | |
| SCHEMBL16952431 | 0.79 | HPGD (0.37) | MAPTALDH1A1POLBHPGDXBP1 | |
| SCHEMBL16951305 | 0.79 | MAPT (0.34) | MAPTALDH1A1POLBHPGDXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |