Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695482 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL11615936 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL1695487 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL7622874 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL7622870 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL1695485 | 0.98 | ESR1 (0.40) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL1695501 | 0.94 | HIF1A (0.42) | ESR1HIF1ASMN1; SMN2RECQLKMT2A | |
| SCHEMBL1695494 | 0.86 | ALOX15 (0.39) | SMN1; SMN2KMT2AGSTP1RAB9AALDH1A1 | |
| SCHEMBL3775177 | 0.85 | GSTP1 (0.37) | SMN1; SMN2KMT2AGSTP1RAB9AALDH1A1 | |
| SCHEMBL1695767 | 0.84 | ALOX15 (0.38) | ESR1SMN1; SMN2KMT2AGSTP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582453-B1 | TRANSESTERIFICATION PROCESS USING MIXED SALT ACETYLACETONATES CATALYSTS | ECOSYNTH NV (BE) | 2016-12-28 | — | — | EP | disclosed |
| US-9309188-B2 | Method for allylating and vinylating aryl, heteroaryl, alkyl, and alkene halogenides using transition metal catalysis | Saitigo GmbH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-8865931-B2 | Transesterification process using mixed salt acetylacetonates catalysts | ECOSYNTH BVBA (BE) | 2014-10-21 | — | — | US | disclosed |
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | SALTIGO GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| CN-103140287-A | Transesterification process using mixed salt acetylacetonates catalysts | ECOSYNTH BVBA | 2013-06-05 | — | — | CN | disclosed |
| EP-2582453-A2 | TRANSESTERIFICATION PROCESS USING MIXED SALT ACETYLACETONATES CATALYSTS | Ecosynth BVBA (BE) | 2013-04-24 | — | — | EP | disclosed |
| US-20130090492-A1 | TRANSESTERIFICATION PROCESS USING MIXED SALT ACETYLACETONATES CATALYSTS | ECOSYNTH BVBA (BE) | 2013-04-11 | — | — | US | disclosed |
| WO-2011157645-A2 | TRANSESTERIFICATION PROCESS USING MIXED SALT ACETYLACETONATES CATALYSTS | ECOSYNTH BVBA (BE) | 2011-12-22 | — | — | WO | disclosed |
| US-20100076217-A1 | ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION | SHOWA DENKO K.K. (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2099563-A1 | ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION | Showa Denko K.K. (JP) | 2009-09-16 | — | — | EP | disclosed |
| WO-2006084892-A2 | PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2006-08-17 | — | — | WO | disclosed |
| US-20050165201-A1 | Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester | BORIACK CLINTON J (US) | 2005-07-28 | — | — | US | disclosed |
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | disclosed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | disclosed |
| EP-1290058-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001088013-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2001-11-22 | — | — | WO | disclosed |
| EP-0428343-B1 | A process for producing an alpha,beta-unsaturated carbonyl compound | NIPPON ZEON CO (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5118863-A | Process for producing an α,β-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0428343-A1 | A process for producing an alpha,beta-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4112235-A | Transesterification of carboxylic acids | UOP INC. (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090492-A1 | TRANSESTERIFICATION PROCESS USING MIXED SALT ACETYLACETONATES CATALYSTS | ACACA, ACACB, ACSL6 | ESR1 1323/4885HIF1A 3621/4885SMN1; SMN2 3991/4885 |
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | VRK2, VRK1, GRK1 | ESR1 3118/4885HIF1A 2870/4885SMN1; SMN2 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.