Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959851 | 0.87 | GABRA1 (0.42) | NPC1TP53RAB9AALDH1A1MEN1 | |
| SCHEMBL16957328 | 0.85 | CYP4F2 (0.42) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16954923 | 0.84 | ELANE (0.38) | NPC1TP53RAB9AMAPTL3MBTL1 | |
| SCHEMBL16956381 | 0.80 | NPC1 (0.48) | NPC1TP53RAB9AALDH1A1KMT2A | |
| SCHEMBL12482259 | 0.79 | GABRA1 (0.45) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL7669246 | 0.78 | ALDH1A1 (0.46) | NPC1TP53RAB9AALDH1A1MEN1 | |
| SCHEMBL16950864 | 0.78 | HCRTR1 (0.45) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL9653476 | 0.78 | CYP4F2 (0.41) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16957573 | 0.78 | CYP4F2 (0.41) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16953799 | 0.78 | KDM4E (0.44) | NPC1TP53RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |