Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950925 | 0.86 | GABRA1 (0.41) | ELANETLR4GSK3AMAPTNPSR1 | |
| SCHEMBL16957325 | 0.85 | NPC1 (0.35) | TLR4GSK3AMAPTNPSR1L3MBTL1 | |
| SCHEMBL16960025 | 0.85 | CA1 (0.39) | ELANEPTGER4PTGER3PTGER2DAO | |
| SCHEMBL16953875 | 0.83 | ELANE (0.37) | ELANETLR4GSK3AMAPTNPSR1 | |
| SCHEMBL16959340 | 0.81 | GABRA1 (0.32) | DAOPTGS2MAPTGABRA1GABRB2 | |
| SCHEMBL16960196 | 0.77 | MEN1 (0.42) | GSK3AMAPTL3MBTL1 | |
| SCHEMBL18263237 | 0.77 | IAPP (0.44) | ELANEMAPTPPARGPPARA | |
| SCHEMBL16959995 | 0.77 | SCN4A (0.38) | TLR4PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL16957571 | 0.77 | CA1 (0.44) | TLR4GSK3AMAPT | |
| SCHEMBL11885014 | 0.77 | CYP4F2 (0.40) | ELANESLC2A1DAOALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |