Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950925 | 0.88 | GABRA1 (0.41) | NPC1TP53RAB9ATLR4ALDH1A1 | |
| SCHEMBL16956195 | 0.85 | PDXK (0.35) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16954362 | 0.85 | ELANE (0.37) | TLR4GSK3AMAPTNPSR1L3MBTL1 | |
| SCHEMBL16957328 | 0.83 | CYP4F2 (0.42) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16954394 | 0.82 | CA1 (0.41) | ALDH1A1PDCD1CD274MAPT | |
| SCHEMBL16959995 | 0.79 | SCN4A (0.38) | TLR4ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL16960196 | 0.79 | MEN1 (0.42) | NPC1RAB9AALDH1A1GSK3AMAPT | |
| SCHEMBL16957571 | 0.79 | CA1 (0.44) | NPC1RAB9ATLR4ALDH1A1GSK3A | |
| SCHEMBL12482259 | 0.78 | GABRA1 (0.45) | NPC1TP53RAB9ACYP4F2CYP4A11 | |
| SCHEMBL16950330 | 0.77 | L3MBTL1 (0.44) | NPC1TP53RAB9ATLR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |