Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950676 | 0.87 | TDP1 (0.40) | MAPTHPGDTDP1L3MBTL1NPC1 | |
| SCHEMBL16953675 | 0.86 | KMT2A (0.38) | MAPTHPGDTDP1L3MBTL1GAA | |
| SCHEMBL12767841 | 0.86 | NPC1 (0.52) | MAPTHPGDTDP1L3MBTL1NPC1 | |
| SCHEMBL16958634 | 0.83 | HPGD (0.43) | MAPTHPGDTDP1L3MBTL1NPC1 | |
| SCHEMBL16955582 | 0.82 | MAPT (0.42) | MAPTHPGDTDP1L3MBTL1NPC1 | |
| SCHEMBL16954938 | 0.82 | MAPT (0.42) | MAPTHPGDTDP1L3MBTL1NPC1 | |
| SCHEMBL16960582 | 0.81 | TAS1R3 (0.43) | MAPTGAALMNAALDH1A1KMT2A | |
| SCHEMBL16951268 | 0.80 | ALDH1A1 (0.46) | MAPTHPGDGAALMNAALDH1A1 | |
| SCHEMBL16955266 | 0.79 | KDM1A (0.45) | L3MBTL1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16959984 | 0.79 | MAPT (0.45) | MAPTTDP1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |