SCHEMBL16954401

SCHEMBL16954401

C=Cc1ccc(Cl)c(CC)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
IDO1 P14902 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
HTR2A P28223 2/20 0.36
SLC6A4 P31645 2/20 0.36
KCNH2 Q12809 2/20 0.36
TRPA1 O75762 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
GAA P10253 1/20 0.35
ALDH3A1 P30838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19222108 0.85 ALDH1A1 (0.36) L3MBTL1ALDH1A1TP53TDP1SLC6A4
SCHEMBL16961426 0.84 ALDH1A1 (0.39) L3MBTL1ALDH1A1TP53TDP1IDO1
SCHEMBL670230 0.82 ALDH1A1 (0.59) L3MBTL1ALDH1A1KDM4ETDP1ALDH3A1
SCHEMBL810315 0.82 ALDH1A1 (0.40) ALDH1A1TP53TDP1TRPA1SLC5A1
SCHEMBL1362573 0.81 TDP1 (0.45) ALDH1A1TP53TDP1GRIN2DGRIN3B
SCHEMBL30767842 0.81 TDP1 (0.45) ALDH1A1TP53TDP1GRIN2DGRIN3B
Ethane SCHEMBL2154475 0.80 ALDH1A1 (0.57) L3MBTL1ALDH1A1KDM4ETDP1ALDH3A1
SCHEMBL809776 0.80 ALDH1A1 (0.39) ALDH1A1TP53TDP1SLC6A4TRPA1
SCHEMBL11043547 0.79 ALDH1A1 (0.42) ALDH1A1TP53TDP1SLC6A4TRPA1
SCHEMBL810266 0.78 ALDH1A1 (0.37) ALDH1A1TP53TDP1TRPA1SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed