Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767842 | 0.84 | TDP1 (0.45) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL1362573 | 0.84 | TDP1 (0.45) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL10417562 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL2313482 | 0.81 | TDP1 (0.42) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL24982506 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL21287940 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL16954401 | 0.79 | L3MBTL1 (0.41) | ALDH1A1TDP1TP53TRPA1TAS1R3 | |
| SCHEMBL16960986 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1TP53TRPA1MAPT | |
| SCHEMBL685611 | 0.79 | TRPA1 (0.52) | ALDH1A1TRPA1ESR1ESR2 | |
| SCHEMBL25673398 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1TP53TRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036528-B1 | BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-01-16 | — | — | EP | claimed |