Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624896 | 0.78 | NOTUM (0.44) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL8291096 | 0.78 | PDE2A (0.50) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL4547917 | 0.78 | TRPA1 (0.50) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL4547922 | 0.78 | NOTUM (0.44) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL16952207 | 0.77 | NOTUM (0.41) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL13122958 | 0.76 | GAA (0.55) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL1660126 | 0.76 | NOTUM (0.43) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL21668188 | 0.76 | PDE3B (0.43) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL12474267 | 0.76 | NOTUM (0.43) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL12883128 | 0.76 | NOTUM (0.43) | NOTUMPDE3BPDE3ARORCS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |