Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624896 | 0.86 | NOTUM (0.44) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL16957528 | 0.79 | AKR1C3 (0.38) | NOTUMPDE3BPDE3AS1PR1AKR1C3 | |
| SCHEMBL16951994 | 0.78 | AKR1C3 (0.44) | NOTUMS1PR1AKR1C3AKR1C2 | |
| SCHEMBL16959210 | 0.78 | NOTUM (0.37) | NOTUMPDE3BPDE3AAKR1C3AKR1C2 | |
| SCHEMBL16955438 | 0.78 | AKR1C3 (0.34) | AKR1C3AKR1C2AR | |
| SCHEMBL16954579 | 0.77 | NOTUM (0.43) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL14569595 | 0.76 | RORC (0.40) | NOTUMPDE3BPDE3ARORCS1PR1 | |
| SCHEMBL16951386 | 0.75 | AKR1C3 (0.36) | PDE3BPDE3AAKR1C3AKR1C2 | |
| SCHEMBL16960228 | 0.75 | RXRA (0.46) | PDE3BPDE3AAR | |
| SCHEMBL4547922 | 0.75 | NOTUM (0.44) | NOTUMPDE3BPDE3ARORCS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |