SCHEMBL16954697

SCHEMBL16954697

C=[C]c1cccc(CC)c1C1CC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.35
GABRB2 P47870 4/20 0.35
C5AR1 P21730 1/20 0.30
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16950823 0.87 HTR2A (0.32) GABRA1
SCHEMBL16958743 0.83 CHRM2 (0.30)
SCHEMBL16957099 0.80 MAP3K14 (0.36)
SCHEMBL16955962 0.77 ALDH1A1 (0.37) GABRA1
SCHEMBL16952817 0.77 GABRA1 (0.39) GABRA1GABRB2NR3C1
SCHEMBL16950404 0.74 HTR2C (0.37)
SCHEMBL16955508 0.74 PDK2 (0.31)
SCHEMBL16952821 0.74 GABRA1 (0.45) GABRA1GABRB2C5AR1
SCHEMBL14785789 0.73 SLC6A2 (0.45)
SCHEMBL27704827 0.73 GABRA1 (0.41) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed