Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953503 | 0.86 | F2RL1 (0.38) | MAPTMPOLMNA | |
| SCHEMBL16950445 | 0.81 | PSEN1 (0.35) | MAPTPKMSMN1; SMN2RIPK1IDO1 | |
| SCHEMBL16951609 | 0.80 | SRC (0.34) | MAPTSMN1; SMN2KDM4ELMNATP53 | |
| SCHEMBL16958707 | 0.80 | ALDH1A1 (0.38) | MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL16958927 | 0.79 | GAA (0.35) | IDO1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16952684 | 0.79 | GABRA1 (0.32) | MAPTSMN1; SMN2LMNAHTTHSD17B10 | |
| SCHEMBL16961288 | 0.79 | MAPT (0.32) | MAPTPKMSMN1; SMN2RIPK1IDO1 | |
| SCHEMBL16956628 | 0.78 | PDE2A (0.40) | MAPTIDO1LMNA | |
| SCHEMBL16955596 | 0.77 | PSEN1 (0.37) | MAPTPKMSMN1; SMN2RIPK1PSEN1 | |
| SCHEMBL21725483 | 0.77 | FFAR1 (0.37) | MAPTPKMSMN1; SMN2RIPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |